Giann Dellosa

Giann is a DPhil candidate of the University of Oxford working on the structural biology of various picornaviruses such as foot-and-mouth disease virus (FMDV), equine rhinitis A virus, and rhinoviruses. He was awarded an Oxford-Pirbright scholarship to work on the structural dynamics of FMDV capsid in relation to its uncoating triggered by exposure to low pH conditions. He is also working on the molecular virology of FMDV to uncover other biochemical cues which could trigger virus uncoating in the Pirbright Institute's biocontainment facility.

He uses single particle analysis using cryoEM along with other biophysical and molecular virology assays to elucidate uncoating mechanisms. 

Previously, he was trained as a vaccinologist (MSc Vaccinology, EMJMD LIVE) and biologist (MSc Biology, University of the Philippines).

Hameed, S. A., Paul, S., Dellosa, G. K. Y., Jaraquemada, D., & Bello, M. B. (2022). Towards the future exploration of mucosal mRNA vaccines against emerging viral diseases; lessons from existing next-generation mucosal vaccine strategies. npj Vaccines, 7(1), 71.

Kelly, J. T., Dellosa, G. K., Newman, J., Hills, R., Mohamed, A. A., Aniscenko, J., ... & Tuthill, T. J. (2024). Induction of neutralising antibodies against conserved rhinovirus capsid protein VP4 depends on presenting VP4 in a virus-like conformation. bioRxiv, 2024-06.