The Division of Structural Biology
Return to on site working updates
During the COVID-19 pandemic, University of Oxford, Wellcome Centre for Human Genetics, Division of Structural Biology is taking measures to prevent the spread of the disease.
Departments are instructed by the University’s Registrar to continue to work from home where possible, and manage the return to on site working, based on the University guidelines for risk assessments and work prioritisation.
This is to restrict contact between individuals as far as possible. The University remains open and operating as far as possible with the following restrictions -
- No public access to the University
- On-site activity permitted where it cannot be undertaken remotely, driven by safety, capacity and other factors such as schools reopening/other changes in government guidelines
- Teaching and assessment are undertaken remotely where possible and, depending on government guidelines, gatherings of staff and students only permitted where essential for teaching and assessment to take place
High-resolution in situ structure determination by cryo-electron tomography and subtomogram averaging using emClarity.
Ni T. et al, (2022), Nature protocols
Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2
Huang K-YA. et al, (2022), THERANOSTICS, 12, 1 - 17
Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity
Steadman D. et al, (2021), Journal of Medicinal Chemistry
Structure, mechanism, and inhibition of Hedgehog acyltransferase.
Coupland CE. et al, (2021), Mol Cell, 81, 5025 - 5038.e10
The Division of Structural Biology (STRUBI) is a research centre of excellence for the study of the molecular and structural basis of biology. Students in STRUBI study a wide range of problems from a structural and mechanistic perspective using a range of structural biology methods including X-ray Crystallography, cryo-electron microscopy, NMR and other biophysical and biochemical methods. For details of the projects available and how to apply, please look under the Studentships tab.