Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
Journal article
Willis NJ. et al, (2022), Journal of medicinal chemistry
An Observational Cohort Study on the Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and B.1.1.7 Variant Infection in Healthcare Workers by Antibody and Vaccination Status
Journal article
Lumley SF. et al, (2022), Clinical Infectious Diseases, 74, 1208 - 1219
IceBreaker: Software for high-resolution single-particle cryo-EM with non-uniform ice
Journal article
Olek M. et al, (2022), Structure, 30, 522 - 531.e4
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
Journal article
Li D. et al, (2022), Commun Biol, 5
Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies
Journal article
Ng WM. et al, (2022), mBio
Peptoid-Directed Formation of Five-Fold Twinned Au Nanostars through Particle Attachment and Facet Stabilization.
Journal article
Jin B. et al, (2022), Angewandte Chemie (International ed. in English)
Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines
Journal article
Wei J. et al, (2022), Nature Medicine
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
Journal article
Dejnirattisai W. et al, (2022), Cell, 185, 467 - 484.e15
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification
Journal article
Baddock HT. et al, (2022), Nucleic Acids Research
High-resolution in situ structure determination by cryo-electron tomography and subtomogram averaging using emClarity.
Journal article
Ni T. et al, (2022), Nature protocols
The C-terminal domains of the PB2 subunit of the influenza A virus RNA polymerase directly interact with cellular GTPase Rab11a.
Journal article
Veler H. et al, (2022), Journal of virology
Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2
Journal article
Huang K-YA. et al, (2022), THERANOSTICS, 12, 1 - 17
Structural Analysis of Retrovirus Assembly and Maturation.
Journal article
Krebs A-S. et al, (2021), Viruses, 14
Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity
Journal article
Steadman D. et al, (2021), Journal of Medicinal Chemistry
Reduced neutralisation of SARS-CoV-2 omicron B.1.1.529 variant by post-immunisation serum.
Journal article
Dejnirattisai W. et al, (2021), Lancet (London, England)
Structure, mechanism, and inhibition of Hedgehog acyltransferase.
Journal article
Coupland CE. et al, (2021), Molecular cell, 81, 5025 - 5038.e10
Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
Dejnirattisai W. et al, (2021)
A structural view of the SARS-CoV-2 virus and its assembly.
Journal article
Hardenbrook NJ. and Zhang P., (2021), Curr Opin Virol, 52, 123 - 134
Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides.
Journal article
Zhang J. et al, (2021), Nat Commun, 12