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Caffeine inhibits Notum activity by binding at the catalytic pocket

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Zhao Y. et al, (2020), Communications Biology, 3

Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

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Zhao Y. et al, (2020), Nature Communications, 11

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.

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Huo J. et al, (2020), Nature structural & molecular biology

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

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Zhou D. et al, (2020), Nature Structural & Molecular Biology, 27, 950 - 958

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

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Huo J. et al, (2020), Cell Host & Microbe, 28, 445 - 454.e6

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

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Huo J. et al, (2020), Nature Structural & Molecular Biology, 27, 846 - 854

Antiepileptic Drug Carbamazepine Binds to a Novel Pocket on the Wnt Receptor Frizzled-8

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Zhao Y. et al, (2020), Journal of Medicinal Chemistry, 63, 3252 - 3260

Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum

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Zhao Y. et al, (2020), Journal of Pineal Research, 68

Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors.

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Atkinson BN. et al, (2020), Bioorganic & medicinal chemistry letters, 30

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2

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Zhou D. et al, (2019), Nature Microbiology, 4, 414 - 419

Structure of the Wnt signaling enhancer LYPD 6 and its interactions with the Wnt coreceptor LRP 6

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Zhao Y. et al, (2018), FEBS Letters, 592, 3152 - 3162

Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs

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Zhao Y. et al, (2018), Journal of Medicinal Chemistry, 61, 4938 - 4945

Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection

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Ren J. et al, (2018), Journal of Medicinal Chemistry, 61, 724 - 733

The crystal structure of human dopamine β-hydroxylase at 2.9 Å resolution

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Vendelboe TV. et al, (2016), Science Advances, 2, e1500980 - e1500980

New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM

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Fadel F. et al, (2015), Acta Crystallographica Section D Biological Crystallography, 71, 1455 - 1470

Production of Cell Surface and Secreted Glycoproteins in Mammalian Cells

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Seiradake E. et al, (2015), 115 - 127

Poly(A) Binding Protein 1 Enhances Cap-Independent Translation Initiation of Neurovirulence Factor from Avian Herpesvirus

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Tahiri-Alaoui A. et al, (2014), PLoS ONE, 9, e114466 - e114466

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