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Publications

Proceedings of the 25th Analytical Ultracentrifugation Workshops and Symposium.

Demeler B. et al, (2023), European biophysics journal : EBJ

Surface plasmon resonance and microscale thermophoresis approaches for determining the affinity of perforin for calcium ions.

Naneh O. et al, (2023), Frontiers in immunology, 14

Cryo‐EM structures of perforin‐2 in isolation and assembled on a membrane suggest a mechanism for pore formation

Yu X. et al, (2022), The EMBO Journal

Perforin-2 clockwise hand-over-hand pre-pore to pore transition mechanism.

Jiao F. et al, (2022), Nature communications, 13

Single molecule tracking the uncoupling of assembly and membrane insertion in Perfringolysin O.

Senior MJT. et al, (2022), The FEBS journal

Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts

Ye M. et al, (2022)

Structural, Functional and Computational Studies of Membrane Recognition by Plasmodium Perforin-Like Proteins 1 and 2.

Williams SI. et al, (2022), Journal of molecular biology, 434

Structures of perforin-2 in solution and on a membrane reveal mechanisms for pore formation

Yu X. et al, (2022)

Editorial: Perforins and Cholesterol-Dependent Cytolysins in Immunity and Pathogenesis.

Munson GP. et al, (2022), Frontiers in immunology, 13

Structural, functional and computational studies of membrane recognition by Plasmodium Perforin-Like Proteins 1 and 2

Williams SI. et al, (2021)

Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling

Griffiths SC. et al, (2021), Nature Communications, 12

Electron microscopy as a critical tool in the determination of pore forming mechanisms in proteins.

Gilbert RJC., (2021), Methods Enzymol, 649, 71 - 102

The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain.

Karia D. et al, (2020), Royal Society open science, 7

Glucocerebrosidase rescues alpha-synuclein from amyloid formation

Barber MS. et al, (2018)

Structures of monomeric and oligomeric forms of the Toxoplasma gondii perforin-like protein 1

Ni T. et al, (2018), Science Advances, 4

Biophysical Approaches to Protein Folding and Disease, a satellite meeting to the IUPAB-EBSA congress

Dalla Serra M. et al, (2018), European Biophysics Journal, 47, 95 - 96

Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope

Rissanen I. et al, (2017), Journal of Virology, 91

Membrane pores: from structure and assembly, to medicine and technology

Gilbert RJC. et al, (2017), Philosophical Transactions of the Royal Society B: Biological Sciences, 372, 20160208 - 20160208

Repurposing a pore: highly conserved perforin-like proteins with alternative mechanisms

Ni T. and Gilbert RJC., (2017), Philosophical Transactions of the Royal Society B: Biological Sciences, 372, 20160212 - 20160212

Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain

Ni T. et al, (2017), Biochemical Journal, 474, 539 - 556

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