Contact information
Research groups
Yuguang Zhao
Instruct Senior Scientist
Recent publications
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Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10
Journal article
Zhao Y. et al, (2020), Nature Communications, 11
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Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Journal article
Zhou D. et al, (2020), Nature structural & molecular biology
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Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.
Journal article
Huo J. et al, (2020), Nature structural & molecular biology
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Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike
Journal article
Huo J. et al, (2020), Cell Host & Microbe
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Antiepileptic Drug Carbamazepine Binds to a Novel Pocket on the Wnt Receptor Frizzled-8
Journal article
Zhao Y. et al, (2020), Journal of Medicinal Chemistry, 63, 3252 - 3260
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Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum
Journal article
Zhao Y. et al, (2020), Journal of Pineal Research, 68
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Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors.
Journal article
Atkinson BN. et al, (2020), Bioorganic & medicinal chemistry letters, 30
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Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2
Journal article
Zhou D. et al, (2019), Nature Microbiology, 4, 414 - 419
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Structure of the Wnt signaling enhancer
LYPD
6 and its interactions with the Wnt coreceptor
LRP
6
Journal article
Zhao Y. et al, (2018), FEBS Letters, 592, 3152 - 3162
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Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs
Journal article
Zhao Y. et al, (2018), Journal of Medicinal Chemistry, 61, 4938 - 4945