Isabel Elliott
Post Doctoral Research Associate
Recent publications
Gas-phase unfolding assay rapidly predicts structure-function relationships in engineered antibodies with tuned flexibilities.
Journal article
Villafuerte-Vega RC. et al, (2026), Nature communications
Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism.
Journal article
Elliott IG. et al, (2025), Nature communications, 16
Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Journal article
Orr CM. et al, (2022), Science immunology, 7