The mission of the Structural Biology Laboratory (STRUBI) at the University of Oxford is to advance our understanding of fundamental biological processes through the study of macromolecular structures and mechanisms, including proteins, viruses, nucleic acids, and their complexes. STRUBI employs a combination of advanced structural biology techniques, alongside biochemical and computational approaches, to tackle critical questions in molecular and cellular biology, with a focus on health and disease. The laboratory's research is particularly centred on two main themes: host-virus interactions and cell surface signalling assemblies.

STRUBI encompasses the Oxford Particle Imaging Centre (OPIC), which was designed as one of the first facilities worldwide to house state of the art cryo electron microscopy and tomography within BL3 containment.

STRUBI is a sub-department of the Nuffield department of Medicine within the university of Oxford. We share the Henry Wellcome building with CHG and COI

STRUBI’s mission aligns with the overarching goals of Oxford’s Nuffield Department of Medicine and the Medical Research Council (MRC), which emphasize the integration of structural biology into translational research, fostering innovations that benefit both basic science and clinical applications.