Ng WM., Sahin M., Krumm SA., Seow J., Zeltina A., Harlos K., Paesen GC., Pinschewer DD., Doores KJ., Bowden TA.

The GP1 subcomponent of the New World arenavirus GP is a primary target of the neutralizing antibody response, which has been shown to be effective in the prevention and treatment of infection. Here, we characterize the structural basis of the antibody-mediated immune response that arises from immunization of mice against Junín virus and Machupo virus, two rodent-borne zoonotic New World arenaviruses.

Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies

Ng WM., Sahin M., Krumm SA., Seow J., Zeltina A., Harlos K., Paesen GC., Pinschewer DD., Doores KJ., Bowden TA.

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