Strubi Profile

Steinar Halldorsson

Student

The focus of my DPhil is to determine the entry mechanism of phleboviruses such as the Rift Valley fever virus (RVFV) and sever fever with thrombocytopenia syndrome virus (SFTSV). I am working towards obtaining a sub-nm cryo-EM map of the whole RVFV and atomic detailed maps of envelope glycoproteins from the phlebovirus family via X-ray crystallography. Ultimately I hope to describe how the surface glycoproteins are arranged on the surface of the virus and how they facilitate binding to the host cell and entry into the cytosol by membrane fusion.