Dr. Christian Siebold's team will use the funding to study the dynamics of the Hedgehog signalling pathway, a key player in development and stem cell regulation. By combining state-of-the art structural biology techniques and super-resolution fluorescence microscopy he aims to unravel the spatial and temporal processes within the primary cilium, the Hedgehog signalling antenna. Dr. Juha Huiskonen's team studies the host-cell entry of Bunyaviruses, especially Rift Valley fever virus. With the help of ERC funding, Huiskonen's team will use different bio-imaging methods, especially electron cryomicroscopy, tomography and advanced light microscopy, to elucidate the membrane fusion mechanism in these viruses at high spatial and temporal resolution.
Major grants to Strubi investigators
5 March 2015
Two investigators based in the Division of Structural Biology have been awarded prestigious European Research Council (ERC) consolidator grants each of approximately € 2 million. These grants support outstanding researchers at the career stage at which they are consolidating their own independent research programmes.