The Division of Structural Biology (STRUBI) is part of the Nuffield Department of Clinical Medicine (NDM) at the University of Oxford. STRUBI is also part of the Wellcome Trust Centre for Human Genetics. The Division includes the Oxford Protein Production Facility (OPPF) and the Oxford Particle Imaging Centre (OPIC).
STRUBI is situated in the Old Road Campus in the Headington area of Oxford. The Division applies the techniques of structural biology, particularly macromolecular crystallography and electron microscopy, to the study of biomedically important processes. The research interests of the Division include the structural study of viral proteins and intercellular recognition. The work of the laboratory is supported by many sources, but principally the MRC, Cancer Research UK, the BBSRC, the Royal Society, the EU FP6 & FP7 and the Wellcome Trust.
The OPPF
is an MRC-funded project to develop methods and automation for high-throughput structural
proteomics studies of medically important targets. It is particularly focused on protein
production, purification and crystal growth. The OPPF is currently located in a dedicated
building adjacent to STRUBI, but in early 2010 the OPPF will become a national facility and
relocate to the new Research Complex at Harwell.
The OPIC is located in the Henry Wellcome Building for Particle Imaging.
This Wellcome Trust-funded facility allows scientists to study macromolecular complexes, such as human and
animal viruses, in their native cellular environment using a range of structural and biophysical tools.
The facility houses state-of-the-art laboratories at ACDP Cat 3 and DEFRA 4 levels of containment.
allowing study of viruses that are important to human health worldwide, such as HIV and Dengue virus.
Postgraduate study within the Division of Structural Biology is possible as part of several different programmes of research.
The fee charged for study in STRUBI is the lower standard bioscience fee and the costs of fees and maintenance may be covered by a range of financial awards.
For details of major studentship schemes which provide support for post-graduate study in STRUBI, look under the Studentships tab.
Keep in touch with the latest developments
in the Division - or browse the archives.
LATEST: The new-look STRUBI website went live on 28th October. Please email the webmaster with any errors or comments!
To find all the stories, look under the News tab.
The Division of Structural Biology is a
leading player in efforts to coordinate European structural biology. The Division has a five-member team dedicated
to working with the senior academics in the Division to foster international collaboration and help to realize
the goal of integrated large-scale structural biology resources across Europe. These resources would grant access
to all European researchers to allow them to contribute to world-leading research.
For details of the projects in which STRUBI is involved see the Europe tab.
Up to date information about pandemic influenza
for University staff can be found at www.ox.ac.uk/flu.
